Recombinant Human ILT6/LILRA3 protein (His tag)
Product Specifications
Background
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.
Abbreviation
ILT6; LILRA3
Synonyms
CD85 antigen-like family member E; CD85e; HM31; HM43; ILT-6; ILT6; Immunoglobulin-like transcript 6; LIR-4; LIR-4 and Monocyte inhibitory receptor HM43/HM31; Leukocyte immunoglobulin-like receptor 4; Leukocyte immunoglobulin-like receptor subfamily A member 3
UniProt
Q8N6C8
Accession Number
Q8N6C8
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Glu439
Field of Research
Immunology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
48.2 kDa
Observed Molecular Weight
65 kDa
Species
Human
Available Sizes
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