Recombinant Human ILT6/LILRA3 protein (His tag)

Product Specifications

Background

Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.

Abbreviation

ILT6; LILRA3

Synonyms

CD85 antigen-like family member E; CD85e; HM31; HM43; ILT-6; ILT6; Immunoglobulin-like transcript 6; LIR-4; LIR-4 and Monocyte inhibitory receptor HM43/HM31; Leukocyte immunoglobulin-like receptor 4; Leukocyte immunoglobulin-like receptor subfamily A member 3

UniProt

Q8N6C8

Accession Number

Q8N6C8

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Glu439

Field of Research

Immunology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.