Recombinant Human FCGR1A/CD64 protein (His tag)
Product Specifications
Background
CD64 (FcγRI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors FcγRII and FcγRIII. It is normally expressed on the surfaces of monocytes and macrophages.
Abbreviation
FCGR1A; CD64
Synonyms
CD antigen CD64; Fc-gamma RI; Fc-gamma RIA; FcRI; FcgammaRIa; High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I
UniProt
P12314
Accession Number
P12314
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Pro288
Field of Research
Immunology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/l8pmho
Product MSDS
https://789.bio/eb/jz94a1
Calculated Molecular Weight
31.6 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
Curated Selection
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