Recombinant Human ADAM8/CD156a protein (His tag)
Product Specifications
Background
ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. It can be activated and assayed under the conditions described in the Activity Assay Protocol.
Abbreviation
ADAM8; CD156a
Synonyms
ADAM 8; CD antigen CD156a; Cell surface antigen MS2; Disintegrin and metalloproteinase domain-containing protein 8; EC 3.4.24.; MS2
UniProt
P78325
Accession Number
P78325
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Ser653
Field of Research
Cell biology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
71.7 kDa
Observed Molecular Weight
60 kDa
Species
Human
Available Sizes
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