Recombinant Human Interferon α-1/IFNA1 Protein (His Tag)

Product Specifications

Background

Interferon alpha-1/13 (IFN-alpha-1/13 for short), also known as Interferon alpha-D, is a secreted protein which belongs to the alpha/beta interferon family. It is produced by macrophages. IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha exerts a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases.

Abbreviation

Interferon α-1; IFNA1

Synonyms

IFN-alpha-1/13; IFNA1; IFNA13; Interferon alpha-1/13; Interferon alpha-D; LeIF D

UniProt

P01562

Accession Number

P01562

Expression System

HEK293 Cells

Tag

C-His

Sequence

Cys24-Glu189

Field of Research

Cancer; immunology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.