YSK 12C4

YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND) . YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines[1].

Product Specifications

CAS Number

[1829511-70-7]

UNSPSC

12352211

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ysk-12c4.html

Purity

98.31

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCN(C)C)(O)CCCCCCCC/C=C\C/C=C\CCCCC

Molecular Formula

C43H81NO

Molecular Weight

628.11

References & Citations

[1]Nakamura T, et al. Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines. Sci Rep. 2016 Nov 28;6:37849.