YSK 12C4
YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND) . YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines[1].
Product Specifications
CAS Number
1829511-70-7
UNSPSC
12352211
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ysk-12c4.html
Purity
98.31
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCN(C)C)(O)CCCCCCCC/C=C\C/C=C\CCCCC
Molecular Formula
C43H81NO
Molecular Weight
628.11
References & Citations
[1]Nakamura T, et al. Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines. Sci Rep. 2016 Nov 28;6:37849.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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