Recombinant Human FSH-b protein (His tag)
Product Specifications
Background
Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) .
Abbreviation
FSH-b
Synonyms
FSH-B; FSH-Beta; FSHB; Follicle-Stimulating Hormone Beta Subunit; Follitropin Beta Chain; Follitropin Subunit Beta
UniProt
P01225
Accession Number
P01225
Expression System
E.coli
Tag
C-His
Sequence
Met1-Glu129
Field of Research
Signal Transduction; Cancer; Developmental Biology; metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.1 kDa
Observed Molecular Weight
28 kDa
Species
Human
Available Sizes
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