TCMCB07 (TFA)
TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia[1].
Product Specifications
UNSPSC
12352209
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tcmcb07-tfa.html
Purity
99.69
Solubility
DMSO : ≥ 100 mg/mL
Smiles
N/C(N)=N/CCC[C@@H](C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@H](C(NC(C(N3[C@@H](C(N)=O)CCC3)=O)C(C)C)=O)CCCCNC(C[C@@H]4NC([C@H](CCCC)NC(C)=O)=O)=O)=O)=O)NC([C@@H](CC5=CC=C(C=CC=C6)C6=C5)NC([C@H](CCC7)N7C4=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C63H87N15O11.xC2HF3O2
Molecular Weight
1230.46 (free base)
References & Citations
[1]Yongjun Hu, et al. Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07. J Cachexia Sarcopenia Muscle. 2020 Dec;11 (6) :1677-1687.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRC-H702015-25MG 25 mg
N-Hydroxy-L-pipecolic Acid Sodium Salt (~90%)
Sign In for Pricing
View Details 
E-BC-K861-M-01 48 T (46 samples)
Lipoxygenase (LOX) Activity Assay Kit
Sign In for Pricing
View Details E-BC-K861-M-02 96 T (94 samples)
Lipoxygenase (LOX) Activity Assay Kit
Sign In for Pricing
View Details