TC HSD 21
TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].
Product Specifications
CAS Number
[330203-01-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tc-hsd-21.html
Purity
99.0
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C1N(C2=CC=C(OC)C=C2)C(S/C1=C\C3=CC=C(O)C(Br)=C3)=S
Molecular Formula
C17H12BrNO3S2
Molecular Weight
422.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Harada K, et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :504-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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