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(KO Validated) FGF2 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Abbreviation

FGF2

UniProt

P09038

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human FGF2

Target

FGF2; BFGF; FGF-2; FGFB; HBGF-2; fibroblast growth factor 2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cardiovascular; Developmental Biology; Neuroscience; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/lidgk0

Product MSDS

https://789.bio/eb/zjv5uL

Calculated Molecular Weight

17kDa/21kDa/22kDa/30kDa

Observed Molecular Weight

18KDa/22KDa/24KDa

Isotype

IgG

Available Sizes

Curated Selection

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