SLC7A11/xCT Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Abbreviation
SLC7A11/xCT
UniProt
Q9UPY5
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human SLC7A11/xCT
Target
SLC7A11; CCBR1; xCT
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/mum9gc
Product MSDS
https://789.bio/eb/OGynLO
Calculated Molecular Weight
55kDa
Observed Molecular Weight
55KDa
Isotype
IgG
Available Sizes
Curated Selection
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