Amfenac (Sodium Hydrate)

Amfenac Sodium Hydrate is a COX-2 inhibitor.

Product Specifications

CAS Number

[61618-27-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Amfenac_Sodium_Hydrate.html

Purity

98.33

Solubility

DMSO : 150 mg/mL (ultrasonic; warming) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O[Na])CC1=CC=CC(C(C2=CC=CC=C2)=O)=C1N.[H]O[H]

Molecular Formula

C15H14NNaO4

Molecular Weight

295.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Marshall JC, et al. The effects of a cyclooxygenase-2 (COX-2) expression and inhibition on human uveal melanoma cell proliferation and macrophage nitric oxide production. J Carcinog. 2007 Nov 27;6:17.|[2]Matsumoto T, et al. Effect of a non-steroidal anti-inflammatory drug (amfenac sodium) on polymorphonuclear leukocytes. Pharmacol Res Commun. 1982 Jun;14 (6) :523-32.