Neomycin (sulfate)
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis[1][2].
Product Specifications
CAS Number
1405-10-3
UNSPSC
12352005
Hazard Statement
H317, H334
Target
Antibiotic; Bacterial; Phospholipase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Neomycin-sulfate.html
Purity
99.86
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 250 mg/mL (ultrasonic)
Smiles
Molecular Formula
C23H52N6O25S3
Molecular Weight
908.88
Precautions
H317, H334
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Aminoglycoside
Citation 01
Available Sizes
Frequently Asked Questions
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