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FOSB Polyclonal Antibody

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

FOSB

UniProt

P53539

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human FOSB

Target

FOSB; AP-1; G0S3; GOS3; GOSB

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

15kDa/20kDa/26kDa/27kDa/30kDa/31kDa/35kDa

Observed Molecular Weight

38KDa/48KDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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