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Beraprost (sodium)

Beraprost sodium (TRK-100), a prostacyclin analog, is a stable and orally active proagent of PGI2. Beraprost sodium (TRK-100) is a potent vasodilator, has the potential for pulmonary arterial hypertension treatment through expanding renal vessels, improving microcirculation[1]. Beraprost sodium (TRK-100) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

496807-11-5

Product Name Alternative

TRK-100; ML 1129 (sodium)

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rac-beraprost-sodium.html

Purity

99.57

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

CC#CCC([C@@H](/C=C/[C@@H]1[C@]2(C3=CC=CC(CCCC(O[Na])=O)=C3O[C@]2(C[C@H]1O)[H])[H])O)C

Molecular Formula

C24H29NaO5

Molecular Weight

420.47

References & Citations

[1]Li S, et al. Beraprost sodium mitigates renal interstitial fibrosis through repairing renal microvessels.J Mol Med (Berl) . 2019 Jun;97 (6) :777-791.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

IP

Available Sizes

Frequently Asked Questions

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