LY 186126
LY 186126 a Indolidan analog, is a phosphodiesterase (PDE) inhibitor. LY 186126 binds to cardiac sarcoplasmic reticulum PDE with high affinity, with a Kd of 5.6 nM[1].
Product Specifications
CAS Number
100644-00-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ly-186126.html
Smiles
O=C1N(C)C2=C(C=C(C(C(C)C3)=NNC3=O)C=C2)C1(C)C
Molecular Formula
C16H19N3O2
Molecular Weight
285.34
References & Citations
[1]T Ashikaga, et al. Comparison of indolidan analog binding sites of drug antibody and sarcoplasmic reticulum with inhibition of cyclic AMP phosphodiesterase. J Recept Signal Transduct Res. 1996 Sep-Nov;16 (5-6) :315-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC421843 20 µg
Striatin 4 (STRN4) (NM_001039877) Human Over-expression Lysate
Sign In for Pricing
View Details 
