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Recombinant Vinculin Monoclonal Antibody

Product Specifications

Background

Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin) -binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It plays an important role in cell morphology and locomotion.

Abbreviation

Vinculin

UniProt

P18206

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human Vinculin

Target

CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; OTTHUMP00000019861; OTTHUMP00000019862; VCL; VINC; VINC; Vinculin

Clonality

Monoclonal

Clone

R09-1F3

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Cardiovascular; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:200

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

124kDa

Observed Molecular Weight

124kDa

Isotype

IgG

Available Sizes

Curated Selection

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