Recombinant Trk B Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Abbreviation
Trk B
UniProt
Q16620
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant protein of human TrkB
Target
NTRK2; GP145-TrkB; TRKB; trk-B; TrkB; OBHD
Clonality
Monoclonal
Clone
R01-8H1
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Metabolism; Neuroscience
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:5000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
92kDa
Observed Molecular Weight
120-140kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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