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Recombinant Trk B Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Abbreviation

Trk B

UniProt

Q16620

Host

Rabbit

Reactivity

Rat

Immunogen

Recombinant protein of human TrkB

Target

NTRK2; GP145-TrkB; TRKB; trk-B; TrkB; OBHD

Clonality

Monoclonal

Clone

R01-8H1

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Metabolism; Neuroscience

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:1000-1:5000

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

92kDa

Observed Molecular Weight

120-140kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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