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Recombinant Survivin Monoclonal Antibody

Product Specifications

Background

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Abbreviation

Survivin

UniProt

O15392

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human Survivin

Target

API4; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; Apoptosis inhibitor4; Baculoviral IAP repeat containing 5; Baculoviral IAP repeat containing protein 5; Baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; BIRC5; EPR 1; IAP4; Survivin variant 3 alpha; SVV; TIAP

Clonality

Monoclonal

Clone

R04-1B1

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cancer; Cell Biology; Neuroscience

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IF 1:20-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

16kDa

Observed Molecular Weight

16kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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