Recombinant Prohibitin Monoclonal Antibody
Product Specifications
Background
Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
Abbreviation
Prohibitin
UniProt
P35232
Host
Rabbit
Reactivity
Human; Rat
Immunogen
A synthetic peptide of human Prohibitin
Target
Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB; PHB1; Prohibitin
Clonality
Monoclonal
Clone
R07-2G1
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Tags and Cell Markers
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa
Observed Molecular Weight
30 kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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