Recombinant PKR Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Abbreviation
PKR
UniProt
Q03963
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
Recombinant protein of mouse PKR
Target
EIF2AK2; EIF2AK1; PKR; PPP1R83; PRKR; Eif2ak2
Clonality
Monoclonal
Clone
R04-3F2
Conjugation
Unconjugated
Applications
WB
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62kDa
Observed Molecular Weight
74kDa
Isotype
IgG
Available Sizes
Documents
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