Recombinant p53 Monoclonal Antibody
Product Specifications
Background
TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.
Abbreviation
P53
UniProt
P04637
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human p53
Target
Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53
Clonality
Monoclonal
Clone
R07-6A7
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IF 1:20-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44kDa
Observed Molecular Weight
53kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0223523422001350
Isotype
IgG
Available Sizes
Documents
Curated Selection
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