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Recombinant P2Y12 Monoclonal Antibody

Product Specifications

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8) . Alternative splicing results in multiple transcript variants of this gene.

Abbreviation

P2Y12

UniProt

Q9H244

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide of human P2Y12

Target

P2RY12; ADPG-R; BDPLT8; HORK3; P2T (AC) ; P2Y (12) R; P2Y (AC) ; P2Y (ADP) ; P2Y (cyc) ; P2Y12; SP1999

Clonality

Monoclonal

Clone

R02-2E1

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/eqmmpc

Product MSDS

https://789.bio/eb/y9yvD4

Calculated Molecular Weight

40kDa

Observed Molecular Weight

52kDa

Isotype

IgG

Available Sizes

Curated Selection

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