Recombinant P2Y12 Monoclonal Antibody
Product Specifications
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8) . Alternative splicing results in multiple transcript variants of this gene.
Abbreviation
P2Y12
UniProt
Q9H244
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human P2Y12
Target
P2RY12; ADPG-R; BDPLT8; HORK3; P2T (AC) ; P2Y (12) R; P2Y (AC) ; P2Y (ADP) ; P2Y (cyc) ; P2Y12; SP1999
Clonality
Monoclonal
Clone
R02-2E1
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40kDa
Observed Molecular Weight
52kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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