Recombinant NEDD4 Monoclonal Antibody
Product Specifications
Background
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Abbreviation
NEDD4
UniProt
P46934
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human NEDD4
Target
NEDD4; NEDD4-1; RPF1
Clonality
Monoclonal
Clone
R06-7C3
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Neuroscience; Epigenetics and Nuclear Signaling
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:2000-1:3000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
149kDa
Observed Molecular Weight
115kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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