Recombinant MLH1 Monoclonal Antibody

Product Specifications

Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Abbreviation

MLH1

UniProt

P40692

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human MLH1

Target

COCA 2; COCA2; DNA mismatch repair protein Mlh1; FCC 2; FCC2; hMLH 1; hMLH1; HNPCC 2; HNPCC; HNPCC2; MGC5172; MLH 1; MLH1; MLH1; MutL homolog 1 (E. coli) ; MutL homolog 1; MutL homolog 1 colon cancer nonpolyposis type 2; MutL homolog 1; colon cancer; nonpolyposis type 2 (E. coli) ; MutL protein homolog 1; MutL; E. coli; homolog of;1

Clonality

Monoclonal

Clone

R02-2E8

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:1000-1:2000; IF 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

85kDa

Observed Molecular Weight

85kDa

Isotype

IgG

Available Sizes

Documents

Product Datasheet

Click to open

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

45882156 3x 1.0 µg DNA

SUMO3 CRISPR All-in-one AAV vector set (with saCas9)(Rat)

Ask

View Details

GTR15121475 1 Vial

Lentiviral human C12orf49 shRNA (UAS) - Lentiviral human C12orf49 shRNA (UAS, RFP) (25)

Ask

View Details

NBP2-52684C 0.1 mL

Rabbit Monoclonal TCR alpha Antibody (34) [DyLight 650]

Ask

View Details

MBS6347323-01 0.1 mL

SHARPIN, ID (SHARPIN, SIPL1, Sharpin, Shank-associated RH domain-interacting protein, Shank-interacting protein-like 1) (MaxLight 405)

Ask

View Details

MBS6347323-02 5x 0.1 mL

SHARPIN, ID (SHARPIN, SIPL1, Sharpin, Shank-associated RH domain-interacting protein, Shank-interacting protein-like 1) (MaxLight 405)

Ask

View Details

A51105-100UG 100 µg

ADK Antibody

Ask

View Details