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Recombinant MERTK Monoclonal Antibody

Product Specifications

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

Abbreviation

MERTK

UniProt

Q12866

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide of human MERTK

Target

MERTK; MER; RP38; Tyro12; c-Eyk; c-mer

Clonality

Monoclonal

Clone

R07-6H2

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Neuroscience; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

110kDa

Observed Molecular Weight

210kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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