Recombinant MERTK Monoclonal Antibody
Product Specifications
Background
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
Abbreviation
MERTK
UniProt
Q12866
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human MERTK
Target
MERTK; MER; RP38; Tyro12; c-Eyk; c-mer
Clonality
Monoclonal
Clone
R07-6H2
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Neuroscience; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
110kDa
Observed Molecular Weight
210kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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