Recombinant MCM2 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with mCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Abbreviation
MCM2
UniProt
P49736
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human MCM2
Target
BM28; CCNL 1; CCNL1; CDC like 1; cdc19; CDCL 1; CDCL1; Cell devision cycle like 1; Cyclin like 1; D3S3194; DNA replication licensing factor MCM2; KIAA0030; MCM 2; MCM2; MCM2 minichromosome maintenance deficient 2 mitotin; MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) ; MCM2 minichromosome maintenance deficient 2; mitotin; MCM2; MGC10606; Minichromosome maintenance complex component 2; Minichromosome maintenance deficient 2 (mitotin) ; Minichromosome maintenance deficient 2 mitotin; Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; Mitotin; Nuclear protein BM28; OTTHUMP00000216047; OTTHUMP00000216050
Clonality
Monoclonal
Clone
R08-9H4
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IF 1:50-1:200
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
102kDa
Observed Molecular Weight
125kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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