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Recombinant LXR alpha Monoclonal Antibody

Product Specifications

Background

NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.

Abbreviation

LXR alpha

UniProt

Q13133

Host

Rabbit

Reactivity

Human; Rat

Immunogen

A synthetic peptide of human LXR alpha

Target

NR1H3; LXR-a; LXRA; RLD-1; LXR alpha

Clonality

Monoclonal

Clone

R07-6A4

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:20-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/m9coc8

Product MSDS

https://789.bio/eb/8Gefn1

Calculated Molecular Weight

50kDa

Observed Molecular Weight

50kDa

Isotype

IgG

Available Sizes

Curated Selection

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