Recombinant LXR alpha Monoclonal Antibody
Product Specifications
Background
NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.
Abbreviation
LXR alpha
UniProt
Q13133
Host
Rabbit
Reactivity
Human; Rat
Immunogen
A synthetic peptide of human LXR alpha
Target
NR1H3; LXR-a; LXRA; RLD-1; LXR alpha
Clonality
Monoclonal
Clone
R07-6A4
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:20-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50kDa
Observed Molecular Weight
50kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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