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Recombinant Integrin alpha 5 Monoclonal Antibody

Product Specifications

Background

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes.

Abbreviation

Integrin alpha 5

UniProt

P08648

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

A synthetic peptide of human Integrin alpha 5

Target

CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; Fibronectin receptor; alpha subunit; FNRA; Integrin alpha 5 (fibronectin receptor alpha) ; Integrin alpha-5; Integrin alpha-5 light chain; Integrin alpha-F; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) ; ITA5; Itga5; Very late activation protein 5; alpha subunit; VLA-5; VLA5; VLA5A

Clonality

Monoclonal

Clone

R02-3G4

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Signal Transduction; Stem Cells

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

115kDa

Observed Molecular Weight

150kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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