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Recombinant Glutathione Reductase Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Abbreviation

Glutathione Reductase

UniProt

P00390

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide of human Glutathione Reductase

Target

GLR1; GLUR; Glutathione reductase; Glutathione reductase mitochondrial; Glutathione reductase; mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSHR; GSR; MGC78522

Clonality

Monoclonal

Clone

R08-2E4

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cell Biology; Metabolism; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:2000

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

56kDa

Observed Molecular Weight

51kDa

Isotype

IgG

Available Sizes

Curated Selection

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