Recombinant CLSTN1 Monoclonal Antibody
Product Specifications
Background
Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372; 12498782) . Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476) . Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430) . It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production
Abbreviation
CLSTN1
UniProt
O94985
Host
Rabbit
Reactivity
Human; Mouse; Hamster
Immunogen
A synthetic peptide of human CLSTN1
Target
CST-1; CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2
Clonality
Monoclonal
Clone
R07-8H2
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Neuroscience
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
110kDa
Observed Molecular Weight
110kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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