Recombinant 4E BP1 Monoclonal Antibody
Product Specifications
Background
Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Abbreviation
4E BP1
UniProt
Q13541
Host
Rabbit
Reactivity
Human; Mouse; Rat; Hamster
Immunogen
A synthetic peptide of human eIF4EBP1
Target
4E-BP1;4EBP1;4EBP1; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; Eif4ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Clonality
Monoclonal
Clone
R06-8E6
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Metabolism
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/ppdlcr
Product MSDS
https://789.bio/eb/XjjjDS
Calculated Molecular Weight
13kDa
Observed Molecular Weight
15/20kDa
Isotype
IgG
Available Sizes
Curated Selection
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