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Recombinant PKC beta 2 Monoclonal Antibody

Product Specifications

Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.

Abbreviation

PKC beta 2

UniProt

P05771

Host

Rabbit

Reactivity

Human; Rat

Immunogen

A synthesized peptide derived from human PKC beta 2

Target

PRKCB; PKC-beta; PKCB; PRKCB1; PRKCB2

Clonality

Monoclonal

Clone

R06-0C2

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

77kDa

Observed Molecular Weight

77kDa

Isotype

IgG

Available Sizes

Curated Selection

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