Recombinant Nampt Monoclonal Antibody
Product Specifications
Background
Nicotinamide phosphoribosyltransferase (NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
Abbreviation
Nampt
UniProt
P43490
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human Visfatin
Target
1110035O14Rik; AI314458; AI480535; DKFZP666B131; EC 2.4.2.12; MGC117256; NAmPRTase; Nampt; NAMPT; Nicotinamide phosphoribosyltransferase; PBEF 1; PBEF; PBEF1; Pre B cell colony enhancing factor 1; Pre B cell colony enhancing factor; Pre B cell enhancing factor; Pre-B cell-enhancing factor; Pre-B-cell colony-enhancing factor 1; VF; Visfatin
Clonality
Monoclonal
Clone
R05-4C4
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cardiovascular; Metabolism; Immunology; Neuroscience; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/94kh18
Product MSDS
https://789.bio/eb/inX5K8
Calculated Molecular Weight
56kDa
Observed Molecular Weight
56kDa
Isotype
IgG
Available Sizes
Curated Selection
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