Recombinant Topoisomerase I Monoclonal Antibody
Product Specifications
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Abbreviation
Topoisomerase I
UniProt
P11387
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
A synthetic peptide of human Topoisomerase I
Target
TOP1; TOPI
Clonality
Monoclonal
Clone
R02-2H9
Conjugation
Unconjugated
Applications
WB; IHC-P; IF
Field of Research
Epigenetics and Nuclear Signaling; Cancer
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100; IF 1:50-1:200
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
91kDa
Observed Molecular Weight
91kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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