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Recombinant Hexokinase II Monoclonal Antibody

Product Specifications

Background

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Abbreviation

Hexokinase II

UniProt

P52789

Host

Rabbit

Reactivity

Human; Rat; Hamster

Immunogen

Recombinant protein of human Hexokinase II

Target

DKFZp686M1669; Hexokinase 2; Hexokinase 2 muscle; Hexokinase type II; Hexokinase-2; HK 2; HK II; HK2; HKII; HxK 2; HxK2; HXK2; Muscle form hexokinase

Clonality

Monoclonal

Clone

R06-4F4

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Cardiovascular; Metabolism; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/gpeyad

Product MSDS

https://789.bio/eb/Oi5SmT

Calculated Molecular Weight

102kDa

Observed Molecular Weight

102kDa

Isotype

IgG

Available Sizes

Curated Selection

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