Recombinant Hexokinase II Monoclonal Antibody
Product Specifications
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Abbreviation
Hexokinase II
UniProt
P52789
Host
Rabbit
Reactivity
Human; Rat; Hamster
Immunogen
Recombinant protein of human Hexokinase II
Target
DKFZp686M1669; Hexokinase 2; Hexokinase 2 muscle; Hexokinase type II; Hexokinase-2; HK 2; HK II; HK2; HKII; HxK 2; HxK2; HXK2; Muscle form hexokinase
Clonality
Monoclonal
Clone
R06-4F4
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
102kDa
Observed Molecular Weight
102kDa
Isotype
IgG
Available Sizes
Documents
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