Recombinant GSDMD Monoclonal Antibody
Product Specifications
Background
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Abbreviation
GSDMD
UniProt
P57764
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human GSDMD
Target
DF5L; DFNA5L; FKSG10; GSDMDC1; GSDMD
Clonality
Monoclonal
Clone
R06-5C5
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53kDa
Observed Molecular Weight
53kDa
Isotype
IgG
Available Sizes
Documents
Frequently Asked Questions
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