Recombinant FTO Monoclonal Antibody
Product Specifications
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Abbreviation
FTO
UniProt
Q9C0B1
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human FTO
Target
AlkB homolog 9; ALKBH9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; Fat mass and obesity-associated protein; FATSO; MOUSE; HOMOLOG OF; Fto; FTO; GDFD; KIAA1752; mKIAA1752; Protein fatso
Clonality
Monoclonal
Clone
R06-8G5
Conjugation
Unconjugated
Applications
WB; IHC-P; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:2000-5000; IHC 1:50-1:100; IF 1:20-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58kDa
Observed Molecular Weight
58kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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