Recombinant FAK Monoclonal Antibody
Product Specifications
Background
FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals . It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage . This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
Abbreviation
FAK
UniProt
Q05397
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human FAK
Target
FADK 1; FADK; FAK related non kinase polypeptide; FAK1; FAK1; Focal adhesion kinase 1; Focal adhesion Kinase; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein-tyrosine kinase 2; Ptk2; PTK2 protein tyrosine kinase 2
Clonality
Monoclonal
Clone
R06-6B6
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cardiovascular; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
119kDa
Observed Molecular Weight
125kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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