Recombinant Estrogen Receptor alpha Monoclonal Antibody

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESR1; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*;4;5;6;7*/822 isoform; Estrogen receptor alpha; Estrogen receptor alpha delta 3*;4;5;6;7*;8*/941 isoform; Estrogen receptor alpha delta 3*;4;5;6;7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*;5;6;7*/654 isoform; Estrogen receptor alpha delta 4*;5;6;7;8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; ESTRR; NR3A1; Nuclear receptor subfamily 3 group A member 1