Recombinant Cyclooxygenase 2 Monoclonal Antibody

Product Specifications

Background

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme.

Abbreviation

Cyclooxygenase 2

UniProt

P35354

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human COX2

Target

COX 2; COX-2; COX2; Cyclooxygenase 2; Cyclooxygenase 2b; Cyclooxygenase; Cyclooxygenase-2; Cyclooxygenase2; EC 1.14.99.1; fj02a10; Glucocorticoid-regulated inflammatory cyclooxygenase; Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase; GRIPGHS; hCox 2; Macrophage activation-associated marker protein P71/73; OTTHUMP00000033524; PES-2; PGG/HS; PGH synthase 2; PGH2; PGHS 2; PGHS-2; PGHS2; PHS 2; PHS II; PHS2; Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) ; Prostaglandin endoperoxide synthase 2; Prostaglandin G/H synthase 2; Prostaglandin G/H synthase 2 precursor; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin G/H synthase; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) ; Prostaglandin-endoperoxide synthase 2; PTGS2; ptgs2a; TIS10; TIS10 protein; unp1239; wu:fj02a10

Clonality

Monoclonal

Clone

R04-3I1

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Cardiovascular; Metabolism; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

69kDa

Observed Molecular Weight

69kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S1043661822002286

Citation 02

https://www.sciencedirect.com/science/article/pii/S0024320521012686

Citation 03

https://www.nature.com/articles/s41598-022-04785-z

Citation 04

https://www.sciencedirect.com/science/article/pii/S037887411731841X

Citation 05

https://www.sciencedirect.com/science/article/pii/S0305417921000978

Citation 06

https://link.springer.com/article/10.1007/s12012-023-09780-y

Citation 07

https://link.springer.com/article/10.1007/s11356-019-05420-7

Citation 08

https://link.springer.com/article/10.1186/s12917-020-02448-7

Isotype

IgG

Available Sizes

Documents

Product Datasheet

Click to open

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