Recombinant AKT Monoclonal Antibody
Product Specifications
Background
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
Abbreviation
AKT
UniProt
P31749/P31751/Q9Y243
Host
Rabbit
Reactivity
Human; Mouse; Rat; Hamster
Immunogen
Recombinant protein of human AKT1/2/3
Target
PKB; RAC; PRKBA; PKB-ALPHA; RAC-ALPHA; AKT1 ; AKT2; AKT3
Clonality
Monoclonal
Clone
R04-8A4
Conjugation
Unconjugated
Applications
WB; IHC-P
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56kDa
Observed Molecular Weight
56kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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