Recombinant Lactate Dehydrogenase A Monoclonal Antibody
Product Specifications
Background
LDHA, also named as LDH-M and NY-REN-59, is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Abbreviation
Lactate Dehydrogenase A
UniProt
P00338
Host
Rabbit
Reactivity
Human; Rat
Immunogen
A synthetic peptide of human Lactate Dehydrogenase
Target
Cell proliferation-inducing gene 19 protein; GSD11; L lactate dehydrogenase A chain; l7R2; LDH M; LDH muscle subunit; LDH1; PIG19 Proliferation-inducing gene 19
Clonality
Monoclonal
Clone
R09-9A7
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37kDa
Observed Molecular Weight
37kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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