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Recombinant GSK3 beta Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.

Abbreviation

GSK3 beta

UniProt

P49841

Host

Rabbit

Reactivity

Human; Rat; Hamster

Immunogen

A synthetic peptide of human GSK3 beta

Target

Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B; GSK3beta isoform; Serine/threonine-protein kinase GSK3B

Clonality

Monoclonal

Clone

R09-7G8

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:1000-1:2000

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

47kDa

Observed Molecular Weight

47kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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