Recombinant GSK3 beta Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Abbreviation
GSK3 beta
UniProt
P49841
Host
Rabbit
Reactivity
Human; Rat; Hamster
Immunogen
A synthetic peptide of human GSK3 beta
Target
Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B; GSK3beta isoform; Serine/threonine-protein kinase GSK3B
Clonality
Monoclonal
Clone
R09-7G8
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47kDa
Observed Molecular Weight
47kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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