Recombinant NAT10 Monoclonal Antibody
Product Specifications
Background
NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.
Abbreviation
NAT10
UniProt
Q9H0A0
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant protein of human NAT10
Target
ALP; DKFZp434C116; FLJ10774; FLJ12179; FLJ23850; hALP; KIAA1709; N acetyltransferase 10; N acetyltransferase 10 GCN5 related; N acetyltransferase like; N acetyltransferase like protein; N-acetyltransferase 10; NAT10; NAT10; NET43
Clonality
Monoclonal
Clone
R05-1C8
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IF 1:100-1:200
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
116kDa
Observed Molecular Weight
116kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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