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Recombinant NAT10 Monoclonal Antibody

Product Specifications

Background

NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.

Abbreviation

NAT10

UniProt

Q9H0A0

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Recombinant protein of human NAT10

Target

ALP; DKFZp434C116; FLJ10774; FLJ12179; FLJ23850; hALP; KIAA1709; N acetyltransferase 10; N acetyltransferase 10 GCN5 related; N acetyltransferase like; N acetyltransferase like protein; N-acetyltransferase 10; NAT10; NAT10; NET43

Clonality

Monoclonal

Clone

R05-1C8

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IF 1:100-1:200

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

116kDa

Observed Molecular Weight

116kDa

Isotype

IgG

Available Sizes

Curated Selection

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